Ultra‐widefield and high‐speed spiral laser scanning <scp>OR‐PAM</scp>: System development and characterization
Mohsin Zafar, Rayyan Manwar, Laura Stone McGuire, Fady T. Charbel, Kamran Avanaki
Abstract
Abstract Photoacoustic microscopy (PAM) is a high‐resolution imaging modality that has been mainly implemented with small field of view applications. Here, we developed a fast PAM system that utilizes a unique spiral laser scanning mechanism and a wide acoustic detection unit. The developed system can image an area of 12.5 cm 2 in 6.4 s. The system has been characterized using highly detailed phantoms. Finally, the imaging capabilities of the system were further demonstrated by imaging a sheep brain ex vivo and a rat brain in vivo.
Topics & Concepts
Laser scanningCharacterization (materials science)Materials scienceLaserSpiral (railway)NanotechnologyChemistryOptoelectronicsBiophysicsOpticsEngineeringPhysicsBiologyMechanical engineeringPhotoacoustic and Ultrasonic ImagingThermography and Photoacoustic TechniquesOptical Coherence Tomography Applications