Through regulation of the SIRT1 pathway plant sterol ester of α-linolenic acid inhibits pyroptosis thereby attenuating the development of NASH in mice
Hao Han, Jie Li, Lei Tian, Liyuan Pei, Mingming Zheng
Topics & Concepts
PyroptosisChemistryPropidium iodideSteatosisInflammasomeSterolBiochemistryLinolenic acidCholesterolInflammationFatty acidCell biologyEndocrinologyInternal medicineProgrammed cell deathBiologyApoptosisLinoleic acidMedicineReceptorLiver Disease Diagnosis and TreatmentCholesterol and Lipid MetabolismInflammasome and immune disorders