Catalyst-free, visible-light-promoted S–H insertion reaction between thiols and α-diazoesters
Jingya Yang, Ganggang Wang, Shuwen Chen, Ben Ma, Hongyan Zhou, Menghui Song, Cai Liu, Congde Huo
Abstract
A visible-light-promoted S-H insertion reaction between thiols and α-diazoesters was developed. The reaction proceeded smoothly at room temperature with a broad substrate scope, affording various thioethers in moderate to excellent yields. The catalyst- and additive-free nature, sustainable energy source and mild reaction conditions make this strategy more eco-friendly.
Topics & Concepts
ChemistryCatalysisPhotochemistryVisible spectrumInsertion reactionCombinatorial chemistryMedicinal chemistryOrganic chemistryPhysicsOptoelectronicsCyclopropane Reaction MechanismsSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods