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Interleukin-10 suppression enhances T-cell antitumor immunity and responses to checkpoint blockade in chronic lymphocytic leukemia

Jacqueline R. Rivas, Y Liu, Sara S. Alhakeem, Joseph M. Eckenrode, Francesc Martí, James P. Collard, Yanbin Zhang, Khaled A. Shaaban, Natarajan Muthusamy, Gerhard Hildebrandt, Roger A. Fleischman, L Chen, Jon S. Thorson, Markos Leggas, Subbarao Bondada

2021Leukemia65 citationsDOIOpen Access PDF

Topics & Concepts

Chronic lymphocytic leukemiaCD8Cancer researchCytotoxic T cellT cellImmunologyImmune checkpointInterleukin 2Immune systemImmunotherapyLeukemiaMedicineBiologyIn vitroBiochemistryChronic Lymphocytic Leukemia ResearchCAR-T cell therapy researchImmune Cell Function and Interaction
Interleukin-10 suppression enhances T-cell antitumor immunity and responses to checkpoint blockade in chronic lymphocytic leukemia | Litcius