Chemically and mechanically defined hyaluronan hydrogels emulate the extracellular matrix for unbiased in vivo and in vitro organoid formation and drug testing in cancer
Alexander E. G. Baker, Laura C. Bahlmann, Chang Xue, Yung Hsiang Lu, Allysia A. Chin, Jennifer Cruickshank, David W. Cescon, Molly S. Shoichet
Topics & Concepts
MatrigelIn vivoOrganoidCell biologyCancer cellIn vitroExtracellular matrixTumor microenvironmentCancer researchBiologyChemistryImmunologyCancerImmune systemBiochemistryGeneticsBiotechnologyCancer Cells and MetastasisCellular Mechanics and InteractionsProteoglycans and glycosaminoglycans research