Efficient Solid-Phase Extraction of Neonicotinoid Insecticides from Environmental Water and Drink Samples Using a Postmodified Metal–Organic Framework
Shirong Sun, Qianyun Sun, Feng Liu, Yanfang Zhao, Xiaoli Wang, Hai‐Long Jiang, Na Li, Yongning Wu, Lu Liu, Ru‐Song Zhao
Abstract
Neonicotinoid insecticides (NNIs) are extensively utilized globally because of their efficient and broad-spectrum properties. However, their residues are also extensively distributed in the environment. Herein, MIL-101-SO 3 Na with abundant −NH– and sulfonate groups was synthesized via chloromethylation and nucleophilic substitution postmodification strategies and used to extract NNIs via solid-phase extraction. MIL-101-SO 3 Na was enhanced by introducing C–H···N hydrogen bonds to strengthen interaction forces and −SO 3 Na groups to adjust surface charge and enhance electrostatic attraction. This modification and the substantial specific surface area (998 m 2 ·g –1 ) of the metal–organic framework markedly enhanced the enrichment efficiency of MIL-101. The proposed method based on MIL-101-SO 3 Na exhibited a minimal detection threshold (0.04–0.87 ng·L –1 ), an extensive linear spectrum (1–2000 ng·L –1 ), and notable accuracy (a variation of 3.02–11.8%) in water and drink samples. NNI concentrations between 0.25 and 24.2 ng·L –1 in fruit juice and tea samples were accurately identified using the proposed method, demonstrating its feasibility in practical applications. The postmodification of MIL-101-SO 3 Na is an exceptional and promising approach for the sensitive detection of ultratrace NNI levels in complex matrices.