Conditioned medium of adipose derived Mesenchymal Stem Cells reverse insulin resistance through downregulation of stress induced serine kinases
Avinash Sanap, Ramesh Bhonde, Kalpana Joshi
Topics & Concepts
Insulin resistanceKinaseOxidative stressMesenchymal stem cellGlucose uptakeDownregulation and upregulationAdipose tissueChemistryCell biologyP70-S6 Kinase 1Reactive oxygen speciesp38 mitogen-activated protein kinasesMAPK/ERK pathwayUnfolded protein responseBiologyInsulinEndoplasmic reticulumPI3K/AKT/mTOR pathwayEndocrinologyBiochemistrySignal transductionGeneEndoplasmic Reticulum Stress and DiseaseAdipose Tissue and MetabolismPancreatic function and diabetes