Examining hepatoprotective effects of astaxanthin against methotrexate-induced hepatotoxicity in rats through modulation of Nrf2/HO-1 pathway genes
Razieh Azadian, Adel Mohammadalipour, Mohammad Reza Memarzadeh, Mohammad Hashemnia, Mohammad Hossein Aarabi
Topics & Concepts
Oxidative stressMethotrexatePharmacologyAntioxidantHeme oxygenaseAstaxanthinEnzymeChemistryMedicineHemeBiochemistryInternal medicineCarotenoidChemotherapy-induced organ toxicity mitigationAcute Lymphoblastic Leukemia researchChildhood Cancer Survivors' Quality of Life