Human and mouse PAR4 are functionally distinct receptors: Studies in novel humanized mice
Stephanie A. Renna, James V. Michael, Xianguo Kong, Lin Ma, Peisong Ma, Marvin T. Nieman, Leonard C. Edelstein, Steven E. McKenzie
Topics & Concepts
PlateletGenetically modified mouseReceptorProtease-activated receptorBiologyTransgeneThrombinCell biologyGPVIPlatelet activationFunction (biology)ImmunologyGeneBiochemistryBlood Coagulation and Thrombosis MechanismsPlatelet Disorders and TreatmentsProtease and Inhibitor Mechanisms