Schisandrin B, a dual positive allosteric modulator of GABAA and glycine receptors, alleviates seizures in multiple mouse models
Jun Wu, Miao Zhao, Yuchen Jin, Min Li, Ke-xin Yu, Haibo Yu
Topics & Concepts
PharmacologySchisandra chinensisGABAA receptorGlycine receptorStrychnineIonotropic effectAllosteric modulatorChemistryAllosteric regulationAnticonvulsantPilocarpineEpilepsyReceptorMedicineGlycineBiologyNeuroscienceAmino acidBiochemistryNMDA receptorTraditional Chinese medicineAlternative medicinePathologyNeuroscience and Neuropharmacology ResearchCholinesterase and Neurodegenerative DiseasesMedicinal Plants and Neuroprotection