Instability of therapeutic proteins — An overview of stresses, stabilization mechanisms and analytical techniques involved in lyophilized proteins
Arun Butreddy, Karthik Yadav Janga, Srinivas Ajjarapu, Sandeep Sarabu, Narendar Dudhipala
Topics & Concepts
Protein stabilityFreeze-dryingDenaturation (fissile materials)ChemistryInstabilityNucleationSupercoolingProtein aggregationProcess (computing)ChromatographyBiochemistryComputer scienceThermodynamicsOrganic chemistryMechanicsPhysicsNuclear chemistryOperating systemProtein purification and stabilityTransgenic Plants and ApplicationsMicroencapsulation and Drying Processes