De novo induction of lineage plasticity from human prostate luminal epithelial cells by activated AKT1 and c-Myc
Oh‐Joon Kwon, Li Zhang, Deyong Jia, Zhicheng Zhou, Zhouyihan Li, Michael C. Haffner, John K. Lee, Lawrence D. True, Colm Morrissey, Xin Li
Topics & Concepts
BiologyNeuroendocrine differentiationSOX2Chromogranin ACancer researchProstate cancerProstateNeuroendocrine cellCellular differentiationOrganoidCell biologyCancerImmunologyGeneTranscription factorGeneticsImmunohistochemistryProstate Cancer Treatment and ResearchHippo pathway signaling and YAP/TAZRenal and related cancers