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Oxygenation and A2AR blockade to eliminate hypoxia/HIF-1α-adenosinergic immunosuppressive axis and improve cancer immunotherapy

Katarina Halpin-Veszeleiova, Stephen Hatfield

2020Current Opinion in Pharmacology23 citationsDOI

Topics & Concepts

AdenosinergicHypoxia (environmental)BlockadeMedicineOxygenationAdenosineCancer immunotherapyAdenosine receptorImmunotherapyCancerInternal medicineReceptorChemistryAgonistOrganic chemistryOxygenAdenosine and Purinergic SignalingImmune Cell Function and InteractionNanoplatforms for cancer theranostics
Oxygenation and A2AR blockade to eliminate hypoxia/HIF-1α-adenosinergic immunosuppressive axis and improve cancer immunotherapy | Litcius