Protective effect of combination of anakinra and MCC950 against acute lung injury is achieved through suppression of the NF-κB-mediated-MAPK and NLRP3-caspase pathways
Xiuhong Wang, S. R. Wayne Chen, Lili Zhao, Xiaoyun Shi
Topics & Concepts
AnakinraInflammasomeMedicineMAPK/ERK pathwayPharmacologyNF-κBSignal transductionInflammationImmunologyInternal medicineBiologyDiseaseBiochemistryInflammasome and immune disordersImmune Response and InflammationNF-κB Signaling Pathways