Naturally Occurring Phenols Modulate Vegetative Growth and Deoxynivalenol Biosynthesis in <i>Fusarium graminearum</i>
Safa Oufensou, Virgilio Balmas, Emanuela Azara, Davide Fabbri, Maria Antonietta Dettori, Christoph Schüller, Franz Zehetbauer, Joseph Strauss, Giovanna Delogu, Quirico Migheli
Abstract
expression by the tested compounds. Third, liquid chromatography-tandem mass spectrometry analysis allowed quantification of deoxynivalenol (DON) and its acetylated forms released upon treatment with the phenolic compounds. Altogether, the results confirmed the activity of thymol and an equimolar mixture of thymol-magnolol at 0.5 mM, respectively, in inhibiting DON production without affecting vegetative growth. The medium pH buffering capacity after 72-96 h of incubation is proposed as a further element to highlight compounds displaying trichothecene inhibitory capacity with no significant fungicidal effect.