Pancreatic cancer pathology viewed in the light of evolution
Michaël Noë, Seung‐Mo Hong, Laura D. Wood, Elizabeth D. Thompson, Nicholas J. Roberts, Michael Goggins, Alison P. Klein, James R. Eshleman, Scott E. Kern, Ralph H. Hruban
Abstract
One way to understand ductal adenocarcinoma of the pancreas (pancreatic cancer) is to view it as unimaginably large numbers of evolving living organisms interacting with their environment. This "evolutionary view" creates both expected and surprising perspectives in all stages of neoplastic progression. Advances in the field will require greater attention to this critical evolutionary prospective.
Topics & Concepts
Pancreatic cancerPancreasCancerAdenocarcinomaPancreatic ductal adenocarcinomaPathologyBiologyMedicineEndocrinologyGeneticsPancreatic and Hepatic Oncology ResearchCancer Genomics and DiagnosticsRenal cell carcinoma treatment