Dual activation of AhR and Nrf2 pathways by the natural stilbenoid tapinarof protects against particulate matter-induced skin barrier dysfunction
Chia-Hsuan Lin, Horng-Huey Ko, Jiaye Wu, Han Kwon Chang, Chia‐Hung Yen, Chien‐Chih Chiu, Yih‐Fung Chen
Topics & Concepts
HaCaTAryl hydrocarbon receptorChemistryCell biologyReactive oxygen speciesSkin AgingOxidative stressPhotoagingKeratinocyteHuman skinEpidermal growth factor receptorBarrier functionAdherens junctionSignal transductionAntioxidantBiochemistryBlood–brain barrierViability assayEpidermis (zoology)MediatorPhotoprotectionPro-oxidantCellTranscription factorCancer researchTight junctionNeuroinflammationXenobioticSkin Protection and AgingGenomics, phytochemicals, and oxidative stressAir Quality and Health Impacts