Antiproliferative benzothiazoles incorporating a trimethoxyphenyl scaffold as novel colchicine site tubulin polymerisation inhibitors
Dong‐Jun Fu, Simeng Liu, Fu-Hao Li, Jiajia Yang, Jun Li
Abstract
was a novel colchicine site tubulin polymerisation inhibitor with potential to treat prostate cancer.
Topics & Concepts
TubulinColchicineChemistryMicrotubuleLNCaPIC50Docking (animal)PolymerizationStereochemistryIn vitroBiochemistryCancer cellCancerCell biologyBiologyOrganic chemistryMedicineNursingPolymerGeneticsFerrocene Chemistry and ApplicationsSynthesis and biological activitySynthesis and Biological Evaluation