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BOINPYs: facile synthesis and photothermal properties triggered by photoinduced nonadiabatic decay

Lizhi Gai, Ruijing Zhang, Xiuguang Shi, Zhigang Ni, Sisi Wang, Jun‐Long Zhang, Hua Lü, Zijian Guo

2023Chemical Science33 citationsDOIOpen Access PDF

Abstract

. BOINPY) with a facile one-pot synthesis and high yields. BOINPY derivatives exhibited specific features that fully address the concerns related to the design of PTA. The behavior and mechanism of BOINPYs for generating heat through the conical intersection pathway, which is called PIND, have been well understood through theoretical calculations. After encapsulation into the F127 copolymer, BOINPY@F127 nanoparticles displayed efficient photothermal conversion and performed well in the treatment of solid tumors upon light irradiation with good biocompatibility. This study provides useful theoretical guidance and concrete photothermal chromophores, which offer a versatile strategy embedding tunable properties for the development of diverse high-performance PTA.

Topics & Concepts

Photothermal therapyPhotochemistryMaterials scienceNanotechnologyChemical physicsChemistryPerovskite Materials and ApplicationsNanoplatforms for cancer theranostics2D Materials and Applications
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