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Autoimmune Hemolytic Anemia After mRNA COVID Vaccine

Zainab Fatima, Blair R. A. Reece, J. Suzanne Moore, Robert T. Means

2022Journal of Investigative Medicine High Impact Case Reports28 citationsDOIOpen Access PDF

Abstract

Discussion of the hematologic complications of vaccination for severe acute respiratory syndrome coronavirus-2 (COVID-19) has primarily focused on the development of vaccine-associated immune thrombosis with thrombocytopenia (VITT). Other hematologic complications are uncommon. We report the case of a patient who developed immunoglobulin G (IgG)-mediated autoimmune hemolytic anemia (AIHA) after the Moderna COVID-19 messenger ribonucleic acid (mRNA) vaccine.

Topics & Concepts

MedicineAutoimmune hemolytic anemiaImmunologyVaccinationAntibodyImmune systemHemolytic anemiaCoronavirus disease 2019 (COVID-19)VirologyInternal medicineDiseaseInfectious disease (medical specialty)Blood groups and transfusionHeparin-Induced Thrombocytopenia and ThrombosisSARS-CoV-2 and COVID-19 Research
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