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Tissue-specific mRNA delivery and prime editing with peptide–ionizable lipid nanoparticles

Yi Lin, Mengyao Li, Zijin Luo, Yanan Meng, Yan Zong, Hongyu Ren, Xiaolu Yu, Xiaoqiong Tan, Fan Liu, Tuo Wei, Qiang Cheng

2025Nature Materials34 citationsDOI

Topics & Concepts

PeptidePrime (order theory)NanoparticleNanotechnologyMessenger RNAChemistryMaterials scienceBiophysicsBiochemistryBiologyMathematicsGeneCombinatoricsRNA Interference and Gene DeliveryCRISPR and Genetic EngineeringRNA regulation and disease
Tissue-specific mRNA delivery and prime editing with peptide–ionizable lipid nanoparticles | Litcius