Essential requirement for JPT2 in NAADP-evoked Ca <sup>2+</sup> signaling
Gihan S. Gunaratne, Eugen Brailoiu, Shijun He, Ellen M. Unterwald, Sandip Patel, James T. Slama, Timothy F. Walseth, Jonathan S. Marchant
Abstract
A protein that enables the activation of two-pore channels by NAADP is identified.
Topics & Concepts
ChemistryCell biologySignal transductionBiophysicsBiochemistryBiologyCalcium signaling and nucleotide metabolismAnalog and Mixed-Signal Circuit Design