Design, synthesis and biological evaluation of novel indanone containing spiroisoxazoline derivatives with selective COX-2 inhibition as anticancer agents
Hoda Abolhasani, Afshin Zarghi, Tahereh Komeili Movahhed, Ahmad Abolhasani, Bahram Daraei, Siavoush Dastmalchi
Topics & Concepts
ChemistryCytotoxicityStereochemistryMTT assayDocking (animal)SulfonylIC50EnzymeIn vitroBiochemistryOrganic chemistryAlkylNursingMedicineSynthesis and biological activitySynthesis and Characterization of PyrrolesSynthesis of Organic Compounds