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Asymmetrically Segregated Mitochondria Provide Cellular Memory of Hematopoietic Stem Cell Replicative History and Drive HSC Attrition

Ashwini Hinge, Jingyi He, James Bartram, José Javier, Juying Xu, Ellen Fjellman, Hiromi Sesaki, Tingyu Li, Jie Yu, Mark Wunderlich, James C. Mulloy, Matthew Kofron, Nathan Salomonis, H. Leighton Grimes, Marie-Dominique Filippi

2020Cell stem cell213 citationsDOIOpen Access PDF

Topics & Concepts

BiologyCell biologyMitochondrionStem cellHaematopoiesisHematopoietic stem cellCell divisionMitochondrial fissionCell cycleCellGeneticsHematopoietic Stem Cell TransplantationAcute Myeloid Leukemia ResearchMitochondrial Function and Pathology
Asymmetrically Segregated Mitochondria Provide Cellular Memory of Hematopoietic Stem Cell Replicative History and Drive HSC Attrition | Litcius