Litcius/Paper detail

Genome-based discovery and total synthesis of janustatins, potent cytotoxins from a plant-associated bacterium

Reiko Ueoka, Philipp Sondermann, Stefan Leopold‐Messer, Yizhou Liu, Rei Suo, Agneya Bhushan, Lida Vadakumchery, Ute Greczmiel, Yoko Yashiroda, Hiromi Kimura, Shinichi Nishimura, Yojiro Hoshikawa, Minoru Yoshida, Annette Oxenius, Shigeki Matsunaga, R. Thomas Williamson, Erick M. Carreira, Jörn Piel

2022Nature Chemistry18 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryBacteriaGenomeTotal synthesisComputational biologyDrug discoveryStereochemistryBiochemistryGeneticsGeneBiologyMicrobial Natural Products and BiosynthesisMarine Sponges and Natural ProductsPhytochemical compounds biological activities