Covid-19: UK records first death, as world’s cases exceed 100 000
Elisabeth Mahase
Abstract
Firmly established transplantable C3H/HeJ mammary carcinomas can be inhibited by host challenge with Vibrio cholerae neuraminidase (VCN) treated tumor cells. The effect is totally immunospecific, even VCN-treated tumors bearing shared mammary tumor virus (MTV) antigen cannot induce the regression. Thus, VCN is capable of increasing the immunogenicity of the private, unique-unshared tumor antigens on mammary carcinomas; VCN is incapable of increasing the immunogenicity of the shared MTV associated tumor antigen.
Topics & Concepts
ImmunogenicityVibrio choleraeAntigenNeuraminidaseVirologyVirusMouse mammary tumor virusMedicineImmunologyBiologyCancer researchGeneticsBacteriaSARS-CoV-2 and COVID-19 ResearchHepatitis B Virus StudiesVirus-based gene therapy research