P90 ribosomal S6 kinases: A bona fide target for novel targeted anticancer therapies?
Fani Koutsougianni, Dimitra Alexopoulou, Ayça Üvez, Andromachi Lamprianidou, Evangelia Sereti, Chrisiida Tsimplouli, Elif İlkay Armutak, Konstantinos Dimas
Topics & Concepts
KinaseContext (archaeology)BiologyMAPK/ERK pathwayRibosomal s6 kinaseEffectorCarcinogenesisSignal transductionPhosphorylationCell biologyCancer researchComputational biologyCancerGeneticsProtein kinase BP70-S6 Kinase 1PaleontologyMelanoma and MAPK PathwaysSynthesis and biological activityPI3K/AKT/mTOR signaling in cancer