Understanding chemotherapy-induced intestinal mucositis and strategies to improve gut resilience
Alexander T. Sougiannis, Brandon N. VanderVeen, J. Mark Davis, Daping Fan, E. Angela Murphy
2021American Journal of Physiology-Gastrointestinal and Liver Physiology164 citationsDOIOpen Access PDF
Abstract
Intestinal mucositis, or damage to the intestinal mucosa, is a common side effect of chemotherapy. In this review, we describe the pathobiology of intestinal mucositis that is associated with chemotherapy treatments. In addition, we discuss the efficacy of several potential therapeutic strategies that have shown some potential in alleviating chemotherapies' off-target effects.
Topics & Concepts
MucositisChemotherapyMedicineIntestinal mucosaCancerInternal medicineIntensive care medicineOncologyImmunologyOral health in cancer treatmentNeutropenia and Cancer InfectionsHead and Neck Cancer Studies