Revealing the role of nitroxyl during hepatic ischemia-reperfusion injury with a NIR-II luminescent nanoprobe
Chenchen Li, Wenqiang Bi, Tao Liang, Zhen Li, Zhihong Liu
Abstract
An activatable ratiometric NIR-II nanoprobe was developed to visualize the fluctuation of HNO levels in the HIRI process in vivo . With this probe, we reveal the physiological role of HNO as a product of stress reaction during the HIRI process.
Topics & Concepts
NanoprobeNitroxylIn vivoChemistryBiophysicsPhotochemistryNanotechnologyNanoparticleMaterials scienceBiologyBiotechnologySulfur Compounds in BiologyNanoplatforms for cancer theranosticsMolecular Sensors and Ion Detection