Prophylactic Administration of a Bacteriophage Cocktail Is Safe and Effective in Reducing Salmonella enterica Serovar Typhimurium Burden <i>in Vivo</i>
Quentin Lamy-Besnier, Lorenzo Chaffringeon, Marta Lourenço, Rayford B. Payne, Jimmy T. Trinh, Jennifer A. Schwartz, Alexander Sulakvelidze, Laurent Debarbieux
Abstract
Foodborne bacterial infections cause worldwide economic loss. During an epidemic, the use of antibiotics to slow down the spread of the disease is not recommended because of their side effects on the resident microbiota and the selection of antibiotic-resistant bacteria.
Topics & Concepts
SalmonellaSalmonella entericaMicrobiologyBacteriophageListeria monocytogenesBiologyAntibioticsSerotypeBacteriaPhage therapyLytic cycleOutbreakSalmonella enteritidisEscherichia coliVirologyVirusGeneBiochemistryGeneticsBacteriophages and microbial interactionsViral gastroenteritis research and epidemiologySalmonella and Campylobacter epidemiology