The effectiveness of (R)-ketamine and its mechanism of action differ from those of (S)-ketamine in a chronic unpredictable mild stress model of depression in C57BL/6J mice
Anna Rafało-Ulińska, Agnieszka Pałucha-Poniewiera
Topics & Concepts
KetamineAntidepressantMechanism of actionPharmacologyNMDA receptorPrefrontal cortexPsychologyDrugNeuroscienceMedicineHippocampusChemistryReceptorInternal medicineCognitionIn vitroBiochemistryTreatment of Major DepressionTryptophan and brain disordersStress Responses and Cortisol