Targeted glycan degradation potentiates the anticancer immune response in vivo
Melissa A. Gray, Michal A. Stanczak, Natália Rodrigues Mantuano, Han Xiao, Johan F. A. Pijnenborg, Stacy A. Malaker, Caitlyn L. Miller, Payton A. Weidenbacher, Julia T. Tanzo, Green Ahn, Elliot C. Woods, Heinz Läubli, Carolyn R. Bertozzi
Topics & Concepts
SIGLECCancer researchImmune systemImmune checkpointDruggabilityImmunotherapyCancer immunotherapyDownregulation and upregulationKinomeCancerImmunologyBiologyMedicineSignal transductionCell biologyInternal medicineBiochemistryGeneGlycosylation and Glycoproteins ResearchImmunotherapy and Immune ResponsesMonoclonal and Polyclonal Antibodies Research