Dimethyl itaconate attenuates palmitate-induced insulin resistance in skeletal muscle cells through the AMPK/FGF21/PPARδ-mediated suppression of inflammation
Seung Yeon Park, Hyun Jung Lee, Jin-Ho Song, Yong Kyoo Shin, A.M. Abd El‐Aty, Amer Ramadan, Ahmet Hacımüftüoğlu, Ji Hoon Jeong, Tae Woo Jung
Topics & Concepts
Insulin resistanceAMPKProinflammatory cytokineInternal medicineEndocrinologyFGF21Protein kinase BGlucose uptakeInsulin receptorInflammationChemistrySignal transductionInsulinPhosphorylationBiologyMedicineBiochemistryProtein kinase AReceptorFibroblast growth factorFibroblast Growth Factor ResearchAdipokines, Inflammation, and Metabolic DiseasesMetabolism, Diabetes, and Cancer