Hyaluronic acid-enriched bilosomes: an approach to enhance ocular delivery of agomelatine via D-optimal design: formulation, <i>in vitro</i> characterization, and <i>in vivo</i> pharmacodynamic evaluation in rabbits
Asmaa Ashraf Nemr, Galal Mohamed El-Mahrouk, Hany Abdo Badie
Abstract
pharmacodynamics parameters over the AGO solution, so AGO-loaded bilosome could improve ocular delivery and the bioavailability of agomelatine.
Topics & Concepts
In vivoNiosomeHyaluronic acidPharmacodynamicsDrug deliveryIntraocular pressureMaterials sciencePharmacologyUlcer indexBiomedical engineeringChromatographyChemistryPharmacokineticsVesicleOphthalmologyNanotechnologyMedicineBiologyBiochemistryMembraneStomachAnatomyBiotechnologyGastric mucosaGlaucoma and retinal disordersOcular Surface and Contact LensAdvanced Drug Delivery Systems