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Structural and mechanistic insights into fungal β-1,3-glucan synthase FKS1

Xinlin Hu, Ping Yang, Changdong Chai, Jia Liu, Huanhuan Sun, Yanan Wu, Mingjie Zhang, Min Zhang, Xiaotian Liu, Hongjun Yu, Xiaotian Liu, Hongjun Yu

2023Nature208 citationsDOIOpen Access PDF

Topics & Concepts

Antifungal drugEchinocandinBiochemistryATP synthaseMechanism of actionChemistryMutantEnzymeGlucanBiologyCell biologyCandida albicansAntifungalMicrobiologyIn vitroGeneFluconazolePlant-Microbe Interactions and ImmunityStudies on Chitinases and ChitosanasesEnzyme Production and Characterization
Structural and mechanistic insights into fungal β-1,3-glucan synthase FKS1 | Litcius