3D printing of Rg3-loaded hydrogel scaffolds: anti-inflammatory and scar-formation related collagen inhibitory effects for scar-free wound healing
Xusen Wang, Pengyu Wei, Cewen Hu, Huajing Zeng, Zengjie Fan
Abstract
studies reveal that the composite hydrogel scaffolds effectively accelerate wound healing and achieve scar-free wound healing within three weeks. Histological and immunohistochemical (IHC) analyses show that the composite hydrogel scaffolds reduce the inflammatory response and inhibit excessive collagen accumulation. These combined effects underscore the potential of our approach in effectively inhibiting scar formation.
Topics & Concepts
ScaffoldWound healing3d printedMaterials scienceBiomedical engineeringSurgeryMedicineWound Healing and TreatmentsSurgical Sutures and AdhesivesPeriodontal Regeneration and Treatments