IL4 stimulated macrophages promote axon regeneration after peripheral nerve injury by secreting uPA to stimulate uPAR upregulated in injured axons
Yuki Matsui, Ken Kadoya, Yusuke Nagano, Takeshi Endo, Masato Hara, Gen Matsumae, T. Suzuki, Yasuhiro Yamamoto, Mohamad Alaa Terkawi, Norimasa Iwasaki
Topics & Concepts
AxonRegeneration (biology)Urokinase receptorWallerian degenerationCell biologyMacrophageBiologyNeurosciencePlasminogen activatorAxon guidanceEndocrinologyBiochemistryIn vitroNerve injury and regenerationWound Healing and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms