C–H Bond Functionalization Using Pd- and Au-Supported Catalysts with Mechanistic Insights of the Active Species
Tamao Ishida, Makoto Tokunaga, Zhenzhong Zhang, Haruno Murayama, Eiji Yamamoto
Abstract
Abstract The process of C–H functionalization has been extensively studied as a direct C–C bond-forming reaction with high atomic efficiency. Efforts have also been made on such reactions by using supported catalysts, which are superior in terms of catalyst separation from the reaction mixture and reusability. In this review, an overview of C–H functionalization reactions, especially those involving Pd- and Au-supported catalysts, is presented. In particular, we discuss reaction mechanisms, active species, leaching, reusability, etc. 1 Introduction 2 Types of Supported Metal Catalysts and Their Active Species 3 Modes of C–H Bond Activation 4 Oxidative C–H C–H Coupling of Aryl Compounds 5 C–H C–H Coupling Where One Side Is Aromatic 6 C–H Acylation of Aromatic Compounds and Related Reactions 7 Conclusion