Comparing radiolytic production of H2O2 and development of Zebrafish embryos after ultra high dose rate exposure with electron and transmission proton beams
Houda Kacem, S. Psoroulas, Gaël Boivin, Michael Folkerts, Veljko Grilj, Antony Lomax, Adrien Martinotti, D. Meer, Jonathan Ollivier, Benoît Petit, Sairos Safai, Ricky A. Sharma, Michele Togno, Marta Vilalta, Damien C. Weber, Marie‐Catherine Vozenin
Abstract
The physico-chemical and biological response to conventional and UHDR electron and proton beams was investigated, along with conventional photons. The temporal structure and nature of the beam affected both, with electron beam at ≥1400 Gy/s and proton beam at 0.1 and 1260 Gy/s found to be isoefficient at sparing zebrafish embryos.
Topics & Concepts
ProtonBeam (structure)EmbryoElectronCathode rayRadiochemistryIrradiationDose rateMaterials scienceAtomic physicsChemistryPhysicsOpticsNuclear physicsBiologyCell biologyRadiation Therapy and DosimetryRadiation Effects and DosimetryAdvanced Radiotherapy Techniques