Long-term skin-resident memory T cells proliferate in situ and are involved in human graft-versus-host disease
Johanna Strobl, Ram Vinay Pandey, Thomas Krausgruber, Nadine Bayer, Lisa Kleißl, Bärbel Reininger, Pablo Vieyra-Garcia, Peter Wolf, Maaia Margo Jentus, Margit Mitterbauer, Philipp Wohlfarth, Werner Rabitsch, Georg Stingl, Christoph Bock, Georg Stary
Abstract
GVHD includes an autoinflammatory host-versus-graft component from recipient-derived skin-resident memory T cells.
Topics & Concepts
Graft-versus-host diseaseHost (biology)DiseaseHuman memoryTerm (time)Human diseaseMedicineBiologyIn situImmunologyNeurosciencePathologyChemistryGeneticsPhysicsCognitionQuantum mechanicsOrganic chemistryHematopoietic Stem Cell TransplantationT-cell and B-cell ImmunologyImmune Cell Function and Interaction