PI3K/AKT and MAPK1 molecular changes preceding matrix metallopeptidases overexpression during tamoxifen-resistance development are correlated to poor prognosis in breast cancer patients
Lama Hamadneh, Mohamad Bahader, Rama Abuarqoub, Mohammad Alwahsh, Ala A. Alhusban, Suhair Hikmat
Topics & Concepts
TamoxifenBreast cancerMedicineCancer researchMetastasisOncologyPI3K/AKT/mTOR pathwayInternal medicineCancerBiologySignal transductionGeneticsProtease and Inhibitor MechanismsPeptidase Inhibition and AnalysisHER2/EGFR in Cancer Research