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Efficient and high-fidelity base editor with expanded PAM compatibility for cytidine dinucleotide

Zhiquan Liu, Siyu Chen, Yingqi Jia, Huanhuan Shan, Mao Chen, Yuning Song, Liangxue Lai, Zhanjun Li

2021Science China Life Sciences43 citationsDOI

Topics & Concepts

CytidineCytidine deaminaseComputational biologyBiologyGenome editingGeneMolecular biologyChemistryCRISPRGeneticsBiochemistryEnzymeCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesVirus-based gene therapy research
Efficient and high-fidelity base editor with expanded PAM compatibility for cytidine dinucleotide | Litcius