Rapamycin restrains platelet procoagulant responses via FKBP-mediated protection of mitochondrial integrity
Kamila M. Śledź, Samantha Moore, Tom N. Durrant, Thomas A. Blair, Roger W. Hunter, Ingeborg Hers
Topics & Concepts
mTORC1PI3K/AKT/mTOR pathwayPlateletFKBPSirolimusPharmacologyPlatelet activationChemistryThrombinCell biologyBiologySignal transductionImmunologyBiochemistryPlatelet Disorders and TreatmentsRenal Transplantation Outcomes and TreatmentsSignaling Pathways in Disease