Macrocyclic complexes of Fe(<scp>iii</scp>) with mixed hydroxypropyl and phenolate or amide pendants as T<sub>1</sub> MRI probes
Elizabeth A. Kras, Roy Cineus, Matthew R. Crawley, Janet R. Morrow
Abstract
Fe( iii ) macrocyclic complexes with mixed oxygen donor pendants are studied as T 1 MRI probes. Complexes with a phenolate pendant are among the most promising and produce pH dependent relaxivity profiles consistent with proton exchange pathways.
Topics & Concepts
AmideChemistryProtonStereochemistryPolymer chemistryOxygen atomProton NMRCrystallographyCombinatorial chemistryMoleculeOrganic chemistryQuantum mechanicsPhysicsLanthanide and Transition Metal ComplexesMagnetism in coordination complexesAdvanced MRI Techniques and Applications