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Mathematical Modeling for Prediction Dynamics of the Coronavirus Disease 2019 (COVID-19) Pandemic, Quarantine Control Measures

Din Prathumwan, Kamonchat Trachoo, Inthira Chaiya

2020Symmetry31 citationsDOIOpen Access PDF

Abstract

A mathematical model for forecasting the transmission of the COVID-19 outbreak is proposed to investigate the effects of quarantined and hospitalized individuals. We analyze the proposed model by considering the existence and the positivity of the solution. Then, the basic reproduction number (R0)—the expected number of secondary cases produced by a single infection in a completely susceptible population—is computed by using the next-generation matrix to carry out the stability of disease-free equilibrium and endemic equilibrium. The results show that the disease-free equilibrium is locally asymptotically stable if R0<1, and the endemic equilibrium is locally asymptotically stable if R0>1. Numerical simulations of the proposed model are illustrated. The sensitivity of the model parameters is considered in order to control the spread by intervention strategies. Numerical results confirm that the model is suitable for the outbreak that occurred in Thailand.

Topics & Concepts

Basic reproduction numberOutbreakQuarantineCoronavirus disease 2019 (COVID-19)PandemicEpidemic modelPopulationStability theoryStability (learning theory)MathematicsApplied mathematicsTransmission (telecommunications)DiseaseComputer scienceDemographyBiologyInfectious disease (medical specialty)VirologyMedicineEcologyPhysicsNonlinear systemTelecommunicationsSociologyPathologyMachine learningQuantum mechanicsCOVID-19 epidemiological studiesMathematical and Theoretical Epidemiology and Ecology ModelsSARS-CoV-2 and COVID-19 Research
Mathematical Modeling for Prediction Dynamics of the Coronavirus Disease 2019 (COVID-19) Pandemic, Quarantine Control Measures | Litcius