SUSD2 suppresses CD8+ T cell antitumor immunity by targeting IL-2 receptor signaling
Bao Zhao, Weipeng Gong, Anjun Ma, Jianwen Chen, Maria Velegraki, Hong Dong, Zihao Liu, Lingling Wang, Tamio Okimoto, Devin M. Jones, Yu L. Lei, Meixiao Long, Kenneth J. Oestreich, Qin Ma, Gang Xin, David P. Carbone, Kai He, Zihai Li, Haitao Wen
Topics & Concepts
Cell biologyCD8Cytotoxic T cellBiologyEffectorCancer immunotherapyT cellCytokineAdoptive cell transferIL-2 receptorChimeric antigen receptorImmunotherapyImmune systemCancer researchImmunologyBiochemistryIn vitroImmunotherapy and Immune ResponsesCAR-T cell therapy researchCancer Immunotherapy and Biomarkers