Dihydromyricetin improves LPS-induced sickness and depressive-like behaviors in mice by inhibiting the TLR4/Akt/HIF1a/NLRP3 pathway
Yicong Wei, Yonghong Hu, Keming Qi, Ye Li, Jian‐Xiong Chen, Ruiguo Wang
Topics & Concepts
TLR4NeuroinflammationMicrogliaProtein kinase BInflammasomeIn vivoPharmacologyLipopolysaccharideSickness behaviorTail suspension testBehavioural despair testChemistrySignal transductionBiologyEndocrinologyImmunologyInflammationBiochemistryHippocampusAntidepressantBiotechnologyInflammasome and immune disordersSpondyloarthritis Studies and TreatmentsMedicinal plant effects and applications