Identification of potential inhibitors of cholinergic and β-secretase enzymes from phytochemicals derived from Gongronema latifolium Benth leaf: an integrated computational analysis
Gideon Ampoma Gyebi, Oludare M. Ogunyemi, Ibrahim M. Ibrahim, Olalekan Bukunmi Ogunro, Saheed O. Afolabi, Rotimi J. Ojo, Gabriel O. Anyanwu, Gaber El‐Saber Batiha, Joseph O. Adebayo
Topics & Concepts
ButyrylcholinesteraseChemistryDocking (animal)EnzymeAcetylcholinesteraseMolecular dynamicsBiochemistryPhytochemicalMolecular mechanicsCholinergicStereochemistryAmyloid betaAchéBiologyComputational chemistryNeuroscienceMedicineNursingPeptideCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsEnzyme function and inhibition