Plasmonic Sensing Assay for Long-Term Monitoring (PSALM) of Neurotransmitters in Urine
Wei‐Hsin Chen, Wenting Wang, Qianqi Lin, David‐Benjamin Grys, Marika Niihori, Junyang Huang, Shu Hu, Bart de Nijs, Oren A. Scherman, Jeremy J. Baumberg
Abstract
PSALM, when urine is pretreated by affinity separation. Optimized PSALM enables the long-term monitoring of NT variation in urine in conventional settings for the first time, allowing the development of NTs as predictive or correlative biomarkers for clinical diagnosis.
Topics & Concepts
Detection limitUrineColloidal goldRaman spectroscopySurface-enhanced Raman spectroscopyLinear rangeChromatographyChemistryNanoparticleNanotechnologyMaterials scienceRaman scatteringOpticsPhysicsBiochemistryGold and Silver Nanoparticles Synthesis and ApplicationsSpectroscopy Techniques in Biomedical and Chemical ResearchAdvanced biosensing and bioanalysis techniques