Ubiquitination/de-ubiquitination: A promising therapeutic target for PTEN reactivation in cancer

Ke Wang, Jun Liu, Yunlong Li, Jipeng Li, Rui Zhang

2022Biochimica et Biophysica Acta (BBA) - Reviews on Cancer38 citationsDOI

Topics & Concepts

PTENTensinUbiquitinCancer researchUbiquitin ligaseBiologyTumor suppressor geneCarcinogenesisCancerCell biologySignal transductionGenePI3K/AKT/mTOR pathwayGeneticsPI3K/AKT/mTOR signaling in cancerUbiquitin and proteasome pathwaysCancer, Hypoxia, and Metabolism